Sr. Scientist, Protein Production & Quality Attributes

Working with Us

Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: ~~~/working-with-us .

Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career further than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: ~~~/working-with-us

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In oncology, hematology, immunology, neuroscience, and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. Join us and make a difference.

As part of the Discovery Biotherapeutics efforts at BMS, the Protein Production & Quality Attributes (PPQA) Team plays a key role in producing, delivering, and characterizing a first-in-class and best-in-class Biotherapeutics pipeline. The Sr. Scientist position in Protein Production & Quality Attributes will be located in San Diego (CA), while working with a cross-functional matrix team across two other BMS sites located in Cambridge (MA) and the San Francisco Bay Area (CA). The primary responsibility will be to design, execute LC-MS based workflows in support of characterizing a wide range of biologics drug candidates, including antibody drug conjugates, bispecific and multi-specific antibodies, and other biomolecule formats to progress BMS's robust pipeline that spans multiple disease areas. This role of Sr. Scientist will also be crucial in enabling cross-functional support and collaborations among protein engineering, antibody function & cellular activity, and computational biologics.

Key Responsibilities

In the role, the ideal candidate:

• The successful candidate must be capable of working and operating in a laboratory environment for the entirety of their work schedule.

• Significant past experience in protein mass spectrometry assays, including intact / reduced / subunit mass analysis, peptide mapping, native MS, etc.

• Develop fit-for-purpose analytical assays, operate and maintain LC-MS instruments, independently perform data processing, and communicate domain-specific knowledge / results to general audience.

• Work with multi-disciplinary teams to resolve challenges related to drug discovery, pre-clinical characterizations, developability assessment.

• Champion lab safety, lab organization, results documentation

Basic Qualifications

• Bachelor's Degree with 7+ years of academic and / or industry experience

• OR

• Master's Degree with5+ years of academic and / or industry experience

• OR

• PhD or equivalent advanced degree in the Life Sciences with2+ years of academic and / or industry experience.

Preferred Qualifications

• In-depth knowledge and hands-on experience in various mass spectrometry techniques for protein and antibody characterizations (intact mass analysis, peptide mapping analysis, subunit analysis).

• Experienced in operating LC-MS instruments such as Exploris480 Orbitrap, Bruker MaXis II; experienced with data processing workflows using Protein Metrics, Expressionist, or other equivalent.

• Strong knowledge and experience of lab automation is a plus.

• Hands-on experience working with antibody-drug-conjugate (ADC) is a plus.

• Working knowledge of other analytical techniques such as SEC, IEX, CE-SDS, cIEF is desired.

• Strong fundamental understanding of protein chemistry.

• Working knowledge of bioanalysis.

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as "Transforming patients' lives through science ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to ~~~ . Visit ~~~/ (~~~) eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Company: Bristol-Myers Squibb

Req Number: R1581306

Updated: 2024-05-11 01:58:47.082 UTC

Location: San Diego-CA

Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.